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Story highlights Hillary Clinton compared the anti-vaccine position to questioning whether the sky was blue or the earth was round Some Republican presidential hopefuls have questioned the safety of vaccines and whether they should be required

Clinton is the prohibitive favorite for the Democratic presidential nomination in 2016 and the tweet was seemingly aimed Republican presidential hopefuls who have questioned whether vaccinations should be required and whether they are tied to mental disorders.

Clinton ends the tweet with a nod to her granddaughter, Charlotte, who was born late last year. Clinton regularly used her grandmother status as a rhetorical tool while campaigning for Democrats in 2014.

Federal health officials have expressed concern over a recent measles outbreak that has been fueled by skepticism among some parents of infant vaccination schedules. Measles is a disease that children a regularly vaccinated against.

READ: Chris Christie sidesteps vaccine science

The issue has become political, despite the fact that claims like vaccines leading to childhood autism have been debunked by scientific research.

Sen. Rand Paul of Kentucky questioned the safety of vaccines when he said he had "heard of many tragic cases of walking, talking, normal children who wound up with profound mental disorders after vaccines."

"I'm not arguing vaccines are a bad idea. I think they're a good thing. But I think the parents should have some input," he said during an interview on CNBC.

New Jersey Gov. Chris Christie, when asked about the issue, said that he choose to vaccinate his children, but added, "Parents need to have some measure of choice in things as well, so that's the balance that the government has to decide."

Former Hewlett-Packard CEO Carly Fiorina, who is also exploring a 2016 run, told Buzzfeed that while she thinks vaccinating for the measles makes sense, the decisions should be up to the parents.

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Hillary Clinton trolls GOP with pro-vaccine tweet

Story highlights Hillary Clinton compared the anti-vaccine position to questioning whether the sky was blue or the earth was round Some Republican presidential hopefuls have questioned the safety of vaccines and whether they should be required

Clinton is the prohibitive favorite for the Democratic presidential nomination in 2016 and the tweet was seemingly aimed Republican presidential hopefuls who have questioned whether vaccinations should be required and whether they are tied to mental disorders.

Clinton ends the tweet with a nod to her granddaughter, Charlotte, who was born late last year. Clinton regularly used her grandmother status as a rhetorical tool while campaigning for Democrats in 2014.

Federal health officials have expressed concern over a recent measles outbreak that has been fueled by skepticism among some parents of infant vaccination schedules. Measles is a disease that children a regularly vaccinated against.

READ: Chris Christie sidesteps vaccine science

The issue has become political, despite the fact that claims like vaccines leading to childhood autism have been debunked by scientific research.

Sen. Rand Paul of Kentucky questioned the safety of vaccines when he said he had "heard of many tragic cases of walking, talking, normal children who wound up with profound mental disorders after vaccines."

"I'm not arguing vaccines are a bad idea. I think they're a good thing. But I think the parents should have some input," he said during an interview on CNBC.

New Jersey Gov. Chris Christie, when asked about the issue, said that he choose to vaccinate his children, but added, "Parents need to have some measure of choice in things as well, so that's the balance that the government has to decide."

Former Hewlett-Packard CEO Carly Fiorina, who is also exploring a 2016 run, told Buzzfeed that while she thinks vaccinating for the measles makes sense, the decisions should be up to the parents.

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Hillary Clinton trolls vaccine-deniers

A new poll of the big states with the most influence in picking the next president shows Florida would be a closely fought battleground if Jeb Bush and Hillary Clinton are the Republican and Democratic presidential nominees in 2012.

Florida is a dead heat between Bush and Clinton. She is 10 points ahead of Marco Rubio.

The Quinnipiac University Poll released Tuesday showed Democrat Clinton with 44 percent and Republican Bush with 33 percent. In another hypothetical matchup, Clinton has 49 percent to 39 percent for Rubio, Florida's Republican U.S. senator.

The presidential election is 21 months away, and polling this far in advance largely shows name recognition among voters. The candidates who scored best among Florida voters are the names they're most familiar with: Clinton, the former first lady, former U.S. senator and former secretary of state, and Bush, the former Florida governor and son and brother of two other Bush presidents.

It's a similar pattern in the other two big swing states in which Quinnipiac polled: Ohio, where Gov. John Kasich tied Clinton, and Pennsylvania, where Chris Christie, the governor of neighboring state New Jersey performed better than any of the other Republicans polled.

Unlike Florida, Clinton significantly outpolled Bush and Christie in those other two states.

Florida, though, is the biggest prize in the 2016 presidential election because it's the largest state that could go for either party, awarding 29 electoral votes, more than 10 percent of the total needed to win the presidency.

Given Bush's showing, Peter Brown, assistant director of the Quinnipiac Poll, said Florida was Clinton's "worst state among the three."

OTHER CANDIDATES: While Clinton is tied with Bush in Florida, she is far ahead of the other potential Republican candidates, including 51 percent to 33 percent over Christie, 50 percent to 38 percent over U.S. Sen. Rand Paul of Kentucky, and 51 percent to 34 percent over former Arkansas Gov. Mike Huckabee.

GENDER: Florida women favor Clinton over Bush 50 percent to 41 percent. Men favor Bush 45 percent to 37 percent. Clinton does even better among women when paired against the other possible Republican candidates.

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Hillary Clinton and Jeb Bush tied in Florida; Clinton leads Marco Rubio

Hillary Clinton weighed in on the growing debate over mandatory vaccination late Monday night, writing a forceful statement of support over twitter.

The former secretary of state, who is widely expected to launch a presidential bid for the Democratic nomination later thisyear, made a passing reference to her newborn granddaughter Charlotte in the tweet.

Mandatory vaccination has emerged as a potent political issue among potential 2016 contendors. On Monday, New JerseyGov. Chris Christie, who has been making moves to launch a bid for the GOP nomination, was forced to walk back a call for "balance" on vaccination after critics called his remarks irresponsible. Kentucky Sen. Rand Paul, and doctor and also a Republican presidential contender, on Monday afternoon told radio host Laura Ingraham that he believes most vaccines should be voluntary.

The canditates' comments come after President Obama weighed in Sunday, saying "there is every reason to get vaccinated there arent reasons to not."

Jose DelReal is a blogger for Post Politics.

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Hillary Clinton speaks out in favor of vaccination

The Candidate Likely To Challenge Hillary Clinton
Charles Krauthammer on the Republicans expected to run for President. BillOReilly.com http://www.billoreilly.com/ Fox News: The O #39;Reilly Factor http://www.foxnews.com/on-air/oreilly/index.html...

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The Candidate Likely To Challenge Hillary Clinton - Video