Archive for the ‘Machine Learning’ Category

Application of Immune Infiltration Signature and Machine Learning Model in the Differential Diagnosis and Prognosis of Bone-Related Malignancies -…

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Front Cell Dev Biol. 2021 Apr 15;9:630355. doi: 10.3389/fcell.2021.630355. eCollection 2021.

ABSTRACT

Bone-related malignancies, such as osteosarcoma, Ewings sarcoma, multiple myeloma, and cancer bone metastases have similar histological context, but they are distinct in origin and biological behavior. We hypothesize that a distinct immune infiltrative microenvironment exists in these four most common malignant bone-associated tumors and can be used for tumor diagnosis and patient prognosis. After sample cleaning, data integration, and batch effect removal, we used 22 publicly available datasets to draw out the tumor immune microenvironment using the ssGSEA algorithm. The diagnostic model was developed using the random forest. Further statistical analysis of the immune microenvironment and clinical data of patients with osteosarcoma and Ewings sarcoma was carried out. The results suggested significant differences in the microenvironment of bone-related tumors, and the diagnostic accuracy of the model was higher than 97%. Also, high infiltration of multiple immune cells in Ewings sarcoma was suggestive of poor patient prognosis. Meanwhile, increased infiltration of macrophages and B cells suggested a better prognosis for patients with osteosarcoma, and effector memory CD8 T cells and type 2 T helper cells correlated with patients chemotherapy responsiveness and tumor metastasis. Our study revealed that the random forest diagnostic model based on immune infiltration can accurately perform the differential diagnosis of bone-related malignancies. The immune microenvironment of osteosarcoma and Ewings sarcoma has an important impact on patient prognosis. Suppressing the highly inflammatory environment of Ewings sarcoma and promoting macrophage and B cell infiltration may have good potential to be a novel adjuvant treatment option for osteosarcoma and Ewings sarcoma.

PMID:33937231 | PMC:PMC8082117 | DOI:10.3389/fcell.2021.630355

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Application of Immune Infiltration Signature and Machine Learning Model in the Differential Diagnosis and Prognosis of Bone-Related Malignancies -...

YouTube Introduces Machine Learning Individual Object Recognition on Videos and Facebook Follows Next – Digital Information World

Artificial Intelligence is one of the greatest achievements in the tech world and while machine learning was only limited to reading still frames up until now and is quite efficient in it, the next step being taken in the advancement of machine learning and artificial intelligence is identifying individual objects within video in order to open up new considerations in brand placement, visual effects, accessibility features and more.

The first and successful step taken towards making AI identify individual objects within video was done by Google. Google had been working towards accomplishing this feature for some time now and after a lot of efforts it has now introduced new advances in its YouTube option which includes being able to tag products in that are present in video clips and provide direct links to shop for those products.

This simply means that companies now can tag their products in YouTube videos no matter at what timing it is being displayed, it can tag its product at that specific time. Along with this it will also provide direct shopping options, facilitating broader ecommerce opportunities in the app.

After the successful introduction of this feature in YouTube, Facebook is taking the next step and introducing a similar feature on its platform and the company claims that their feature will be much better at singling out individual objects within video frames.

Facebook explained that they have collaborated with researchers at Inria with whom they have developed a new method called DINO. This method will be used to train Vision Transformers (ViT) with no supervision. The company has claimed that besides setting a new state of the art among self-supervised methods, this approach leads to a remarkable result that is unique to this combination of AI techniques. Facebook further said that their model can discover and segment objects in an image or a video with absolutely no supervision and without being given a segmentation-targeted objective and all this will make this process effectively automated.

Hence that is why the company claims that their feature is the best of the best.

Facebook is still working towards this feature and once it is launched we cannot wait to see if it out does YouTubes similar feature or not. However, we know that both YouTube and Facebook have always delivered their best and therefore we are sure that they will deliver the best this time as well.

Read next:According to the exec, over 60 percent Instagram users are connected to Facebook Messenger

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YouTube Introduces Machine Learning Individual Object Recognition on Videos and Facebook Follows Next - Digital Information World

AI and Machine Learning Operationalization Software Market by Technology Innovations and Growth 2021 KSU | The Sentinel Newspaper – KSU | The…

The AI & Machine Learning Operationalization Software Market report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain. The report provides in-depth analysis of parent market trends, macro-economic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.

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Top LeadingCompaniesof Global AI & Machine Learning Operationalization Software Market areAlgorithmia, Spell, Valohai Ltd, 5Analytics, Cognitivescale, Datatron Technologies, Acusense Technologies, Determined AI, DreamQuark, Logical Clocks, IBM, Imandra, Iterative, Databricks, ParallelM, MLPerf, Neptune Labs, Numericcal, Peltarion, Weights & Biases, WidgetBrainand others.

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Predicting Depression from Hearing Loss Using Artificial… : The Hearing Journal – LWW Journals

The consequences of hearing loss are many, including social isolation1-3 and depression.10-13 The failure of hearing aids to either prevent or improve depression may stem from a complex relationship between hearing loss, depression, and the social dynamism of hearing loss that we have yet to fully understand. To this end, there are several opportunities to explore the relationship between hearing loss and depression. Moreover, there may be utility in identifying depression in patients with hearing loss at the point of care considering the established link between hearing loss and depression.

Shutterstock/Photographee.eu, technology. Hearing loss, mental health.

Using machine learning to predict depression scores (adapted from Crowson et. al., 2020). Technology. Hearing loss, mental health.

The primary objective of our work was to use a predictive approach using machine learning and audiometric data to determine if these data accurately predict patient-reported depression. We hypothesized that an advanced machine learning model may be useful for identifying depression in patients with audiometric data. We also sought to determine if the addition of other clinical and demographic variables combined with the audiometric data would produce further gains in model accuracy.

In our study, we developed a supervised machine learning model using National Health and Nutrition Examination Survey (NHANES) data, composed of subjective and objective audiometric variables and several other health determinant predictors, to predict scores on a validated depression scalethe Patient Health Questionnaire (PHQ-9). The NHANES is a cross-sectional public health survey designed to assess the health and nutrition status of individuals in the United States. NHANES data has been used in numerous research investigations to incorporate the interplay between determinants of health and specific medical conditions.

In a sample of participants from a survey cycle of the NHANES database, our supervised machine learning approach accurately predicted depression scale scores using audiometric and health determinant predictors. The model's most influential audiometric predictors of higher scores on the depression scale were functional dimensions and not objective audiometric testing variables. Among the most influential predictors, half were related to the social dynamics of hearing loss. The remaining predictors associated with depression in hearing loss were related to noise exposure, tinnitus, and objective audiometric testing. When expanding to include predictors ranging from demographics to other medical and health status content, a social context of hearing loss ranked in the top five most influential.

A strong association between social isolation and hearing loss has been demonstrated in adults.1-3 The observation that hearing loss leads to social isolation is intuitive given that hearing loss leads to impaired efficiency of communication. The connection between social isolation and depression is a natural extension as humans are social creatures.

If hearing care professionals treat hearing loss with conventional hearing aid devices, would it be reasonable to expect social isolation and associated depression to improve? Unfortunately, the relationship appears more complex. Prior work has shown that hearing aids do not result in consistent improvement in social isolation11,14 or depression.10-13 Perhaps the disconnect might be explained by noting that hearing amplification exclusively does not address hearing performance in real-life social situations. Basic sound amplification can and does help individuals with hearing loss. More advanced hearing aids incorporate signal processing technologies to better isolate the relevant sounds in noisy environments. Perhaps future research involving hearing aids with enhanced signal processing technology may lead to further insights into the utility of hearing aids to directly augment the social dynamics of hearing loss.

In summary, we found the NHANES dataset is useful for training machine learning models to accurately predict depression scale scores from audiometric data. As many of the variables collected in the NHANES data are the same clinical data we extract from our patients in real-life clinical encounters, such a predictive model could be useful in predicting depression scale scores at the point of care. We found the most influential audiometric predictors of higher scores on the depression scale were functional dimensions of hearing loss and not simply objective audiometric data like thresholds and word recognition scores. Among these influential functional dimensions, our model indicated the specific effect of hearing loss on social relations was particularly powerful. This is an interesting finding, as prior investigations into the effect of hearing aids on depression and social isolation have failed to show a consistent benefit. Simply giving a patient a hearing aid is not a guarantee that social isolation or depression will improve. Thus, our model output puts forth a new hypothesis that simply amplifying sound alone, in general, fails to address or improve the social dynamism of hearing loss. For today's hearing care clinicians, we suggest that recognizing that social aspects of hearing loss may carry more influence on the development or maintenance of depression than previously thought. Moreover, we may need to reimagine our aural rehabilitation strategies to include specific interventions to optimize social dynamics.

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Predicting Depression from Hearing Loss Using Artificial... : The Hearing Journal - LWW Journals

AI, RPA, and Machine Learning How are they Similar & Different? – Analytics Insight

AI, RPA, and machine learning, you must have heard these words echoing in the tech industry. Be it blogs, websites, videos, or even product descriptions, disruptive technologies have made their presence bold. The fact that we all have AI-powered devices in our homes is a sign that the technology has come so far.

If you are under the impression that AI, robotic process automation, and machine learning have nothing in common, then heres what you need to know, they are all related concepts. Oftentimes, people use these names interchangeably and incorrectly which causes confusion among businesses that are looking for the latest technological solutions.

Understanding the differences between AI, ML, and RPA tools will help you identify and understand where the best opportunities are for your business to make the right technological investment.

According to IBM, Robotic process automation (RPA), also known as software robotics, uses automation technologies to mimic back-office tasks of human workers, such as extracting data, filling in forms, moving files, etc. It combines APIs and user interface (UI) interactions to integrate and perform repetitive tasks between enterprise and productivity applications. By deploying scripts which emulate human processes, RPA tools complete autonomous execution of various activities and transactions across unrelated software systems.

In that sense, RPA tools enable highly logical tasks that dont require human understanding or human interference. For example, if your work revolves around inputting account numbers on a spreadsheet to run a report with a filter category, you can use RPA to fill the numbers on the sheet. Automation will mimic your actions of setting up the filter and generate the report on its own.

With a clear set of instructions, RPA can perform any task. But theres one thing to remember, RPA systems dont have the capabilities to learn as they go. If there is a change in your task, (for example if the filter has changed in the spreadsheet report), you will have to manually input the new set of instructions.

The highest adopters of this technology are banking firms, financial services, insurance, and telecom industries. Federal agencies like NASA have also started using RPA to automate repetitive tasks.

According to Microsoft, Artificial Intelligence is the ability of a computer system to deal with ambiguity, by making predictions using previously gathered data, and learning from errors in those predictions in order to generate newer, more accurate predictions about how to behave in the future.

In that sense, the major difference between RPA and AI is intelligence. While these technologies efficiently perform tasks, only AI can do it with similar capabilities to human intelligence.

Chatbots and virtual assistants are two popular uses of AI in the business world. In the tax industry, AI is making tax forecasting increasingly accurate with its predictive analytics capabilities. AI can also perform thorough data analysis which makes identifying tax deductions and tax credits easier than before.

According to Gartner, Advanced machine learning algorithms are composed of many technologies (such as deep learning, neural networks, and natural language processing), used in unsupervised and supervised learning, that operate guided by lessons from existing information.

Machine learning is a part of AI, so the two terms cannot be used interchangeably. And thats the difference between RPA and ML, machine learnings intelligence comes from AI but RPA lacks all intelligence.

To understand better, let us apply these technologies in a property tax scenario. First, you can create an ML model based on a hundred tax bills. The more bills you feed the model, the more accurately it will make predictions for the future bills. But if you want to use the same machine learning model to address an assessment notice, the model will be of no use. You would then have to build a new machine learning model that knows how to work with assessment notices. This is where machine learnings intelligence capabilities draw a line. Where ML fails to recognize the similarities of the document, an AI application would recognize it, thanks to its human-like interpretation skills.

The healthcare industry uses ML to accurately diagnose and treat patients, retailers use ML to make the right products available at the right stores at the right time, and pharmaceutical companies use machine learning to develop new medications. These are just a few use cases of this technology.

No, but they can work together. The combination of AI and RPA is called smart process automation, or SPA.

Also known as intelligent process automation or IPA, this duo facilitates an automated workflow with advanced capabilities than RPA using machine learning. The RPA part of the system works on doing the tasks while the machine learning part focuses on learning. In short, SPA solutions can learn to perform a specific task with the help of patterns.

The three technologies, AI, RPA, and ML, and the duet, SPA hold exciting possibilities for the future. But only when companies make the right choice, the rewards can be reaped. Now that you have an understanding of the various capabilities of these technologies, adapt and innovate.

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AI, RPA, and Machine Learning How are they Similar & Different? - Analytics Insight