Mediaboss Marketing

Officials encourage people to protect themselves from mosquito bites by using bug spray. Harris County Public Health confirmed bug spray is one of the best ways to keep mosquitoes away as warmer weather arrives.

Local health officials say warmer weather means cookouts, swimming, and other outdoor activities, but also means a lot more mosquitoes.

Barbie Robinson is the Harris County Health Executive Director and said the Houston-area has the perfect conditions for a higher risk of mosquito-borne illnesses in humans and animals.

"We're prone to hurricanes, tropical storms, and wet conditions, as well as hot weather," she said. "And these types of conditions lead to an increase in mosquito problems in populations."

Robinson said mosquitos are considered the most dangerous insects in the world because of the way they can spread disease. The West Nile or Zika virus are examples of viruses most prominent in hot and humid areas like Houston.

Other officials warn that this year will likely see more mosquito problems than the last. County Mosquito Control Director Max Vigilant said Houston has seen a fluctuation in mosquito populations for the past few years.

"Usually, when we see this pattern, it's always like a two-year increase," he said. "So I'm looking at 2023, where our numbers may be higher than what 2022 presented to us."

Last year, five cases of mosquito-borne viruses were reported in Harris County. Of the five, one man in his 80s died form the West Nile Virus.

Health officials provided various ways residents can reduce mosquito activity around their homes and avoid mosquito-borne illnesses.

Read more:
Health officials remind Houstonians of ways to reduce mosquito activity around their homes - Houston Public Media

Most of the major U.S. professional sports leagues, plus the media companies Fox and NBCUniversal, are creating an alliance to ensure that sports betting advertising is done responsibly and does not target minors.

The Coalition for Responsible Sports Betting Advertising was created Wednesday, consisting of the National Football League, Major League Baseball, the men's and women's leagues of the National Basketball Association, the National Hockey League, NASCAR, Major League Soccer, Fox and NBCUniversal.

They described the group as a voluntary alliance to control how sports betting advertising, which is ever-present on the airwaves, in print and online, is presented to consumers.

It includes a recommendation that "excessive" advertising be avoided.

Formation of the group follows a move last month by the commercial casino industry through its U.S. national trade association, the American Gaming Association, to adopt a new responsible sports betting marketing code.

Both efforts recognize the proliferation of sports betting advertising in the five years since the U.S. Supreme Court cleared the way for any state to offer legal sports wagering.

They also have a clear, if unstated, goal: to regulate their own advertising before the government might step in and do it for them.

One New York congressman has introduced legislation that would ban all online and digital sports betting advertising, and others have called for government-imposed regulation of sports betting ads.

"As the legalization of sports betting spreads nationwide, we feel it is critical to establish guardrails around how sports betting should be advertised to consumers across the United States," the group said in a joint statement.

"Each member of the coalition feels a responsibility to ensure sports betting advertising is not only targeted to an appropriate audience, but also that the message is thoughtfully crafted and carefully delivered."

David Schwartz, a gambling historian at the University of Nevada Las Vegas, said the prospects forgovernment control of sports betting ads are uncertain.

"I can see how it would be in the leagues' and operators' best interests to avoid formal federal oversight," he said.

"Advertising is an area that touches not just customers, but the public at large. As such, it may have more visibility than even the actual business of taking bets. It is understandable that those involved want to get out in front of this."

Speaking Wednesday at a gambling industry forum in Atlantic City, West Virginia state Delegate Shawn Fluharty said there is definitely concern among state lawmakers over the frequency of sports betting advertising.

"If you're talking to any people out there, they're probably a little tired of seeing Jamie Foxx on TV," he said, referring to the actor's widely broadcast ads for BetMGM's sportsbook.

He said the coalition is a good idea that also shows that the leagues recognize there is cause for concern about the possibility of government intervention regarding sports betting advertising.

The group has several core principles, including that sports betting should be marketed only to adults of legal betting age; that the ads should not promote irresponsible or excessive gambling; they should be in good taste and not be misleading; and that publishers of sports betting advertising should have strong internal reviews and should take seriously complaints from consumers about such advertising.

Kenny Gersh, executive vice-president of media and business development for the MLB, called the group "another important step for our industry as legal sports betting continues to grow."

Sports betting is currently legal in 33 U.S. states, plus Washington, D.C.

"While providing new fan engagement opportunities to enjoy our sport in more ways, we have to continue to be mindful and deliberate with how these sports betting options are presented and to whom they're directed," Gersh said.

"Layering this coalition's work in the advertising arena on top of our efforts to promote responsible gambling and address problem gambling challenges will lead to more thoughtful planning and implementation across the board."

David Highhill, general manager of sports betting for the NFL, said the leagues recognize advertising as an important component of responsible conduct.

"Legalized sports betting offers fans another way to engage with their favourite sports, but just as we must support problem gambling prevention and resourcing, we must also remain mindful of how sports betting is presented and advertised to consumers, and this coalition should greatly aid in that cause," he said.

Mike Mulvihill, an executive vice-president with Fox Sports, said:"We are committed to providing fans a responsible and ethical engagement with sports betting, keeping the integrity of the games and our broadcasts at the forefront at all times."

Keith Whyte, executive director of the U.S. National Council on Problem Gambling, praised the group for "taking steps to lead the industry in proactive change to protect consumers."

More here:
Big U.S. pro sports leagues join alliance pledging responsible ... - CBC.ca

Legislation aims to reform school boards and allow the ministry to set provincial priorities in student achievement

Editor's note: This article originally appeared onThe Trillium, a new Village Media website devoted exclusively to covering provincial politics at Queens Park. The following story has been updated from its original version.

Education Minister Stephen Lecce tabled legislation on Monday to increase provincial control over education, reform how local school boards are governed, and give the province control over excess school properties.

The education minister told the media Monday the changes are about making boards more accountable in order to improve student outcomes.

Lecce read a quote given to the provinces 1995 Royal Commission on Learning about boards being a kingdom unto themselves, with little need to report to parents or to the world at large what they are doing with our kids, and whether theyre doing it successfully, that he said remains true today.

Meanwhile, opposition politicians criticized his bill both as ineffective smoke and mirrors and as a stealth plan to sell off school board assets to the premiers developer friends.

The Better Schools and Student Outcomes Act, if passed, would allow the province to set priorities on student achievement and require school boards to implement and report on those priorities with multi-year Board Improvement Plans.

Lecce said those priorities are a back-to-basics approach that ensures students have the foundational skills in reading, writing and math that they need to succeed in any career.

The bill would require boards to report their progress on those goals publicly. The Ministry of Education will hold them accountable if they fall short, Lecce said.

Boards will also face stricter requirements to report on their spending and be required to cooperate with municipalities on child-care planning once the bill is passed.

Another component of the bill would improve the governance of school boards, Lecce said. The bill would allow the government to establish standardized training for trustees and school board officials to ensure "they have the skills and competencies to deliver on provincial priorities."

It would also require codes of conduct for boards of trustees and create a process under the integrity commissioner to resolve code-of-conduct complaints. The ministry would also be given the power to create a standardized performance appraisal process for directors of education.

The legislation would also give the province regulation-making power to enable the accelerated apprenticeship pathwayalready announcedby the government for consultations beginning in the fall, plus the authority to establish formal guidelines from the curriculum review process.

Lecce was asked if the reform was prompted by two high-profile controversies: a teacher in Halton who attracted worldwide headlines for reportedly wearing huge prosthetic breasts to class and dysfunction and racism at the Peel public board that prompted the province to temporarily seize control of the board.

He responded that there are many examples, and cited the problems in Peel specifically, where the trustees were more interested in personal beefs than putting kids first.

The bill would also allow the Ministry of Education to work with the Ontario College of Teachers and faculties of education on teacher education, expand the eligibility of an Ontario College of Teachers program to support victims of alleged sexual abuse by members, and speed up disciplinary processes in sexual abuse cases.

Another section of the bill proposes to "maximize capital assets" with several new measures.

They include allowing the ministry to direct a school board to sell, or otherwise dispose of, school sites or property if it is not needed to meet current or future student needs. Regulations would be established that would give the province the first right of refusal of that property, to identify if it's needed by another school board covering the same area and, if not, other provincial priorities including long-term care and affordable housing. If it is not needed for those purposes, it would be sold on the open market.

The legislation would also make it easier for schools to be built in multi-use buildings, including condos. It would also set out requirements for joint-use facilities the shared use of school buildings by separate boards after consultations with trustee associations.

It would also require school boards to use particular functional specifications, designs or plans when building, renovating or making additions to schools.

Lecce also announced that base education funding, known as Grants for Student Needs (GSN), will increase by $693 million, a 2.7 per cent increase, putting per-student base funding at $13,125.

The official Opposition seized on that, with NDP education critic Chandra Pasma accusing the government of under-funding education to the point of crisis so it can set the stage for privatization down the road.

The total funding falls $2.5 billion short of where it should be if it had kept pace with inflation since 2018, she said.

We know why our kids are struggling. It's because they are in overcrowded classrooms where they can't get the supports they need after three years of disrupted learning, she said, adding that there are insufficient special education and mental health supports.

But instead of taking responsibility for that and making investments and providing the supports what we have is a bill in which the minister is trying to shift blame to schools, to teachers and school boards for the fact that kids are struggling and he's not providing the investments that they need.

The Liberal and Green parties focused on the parts of the bill that would see the province take over school board properties not needed for education.

It's all about publicly owned, publicly funded, local school board property and the government taking control of that property, said interim Liberal leader John Fraser.

And I don't know about you, but I don't have any confidence in this government when it comes to the public interest in public land when you look at things like the Greenbelt, and Ontario Place. I don't trust them as far as I could throw them.

I'm deeply worried about what they're gonna do with public lands, that they now want to take over control and sell off given what we've seen with the Greenbelt, said Green Leader Mike Schreiner. And so, from my perspective, the priority should be prioritizing student achievement and proper investments in the kinds of supports that students need in our classrooms, not on selling off public land.

Meanwhile, education unions also raised concerns. The Elementary Teachers Federation of Ontario said it was caught off-guard and not consulted on the bill.

Instead of working in partnership to improve our world-renowned education system, the Ford government is focused on creating a crisis in public education where none exists, the union said in a statement. In the governments own materials, they state that Ontario is among the top-performing education systems nationally and internationally. So why is an overhaul necessary? What is their agenda? A refocusing of the education system should not include government overreach.

Ontario Secondary School Teachers' Federation (OSSTF) president Karen Littlewood said she believes the government is trying to monetize education by selling off schools, which its playing with like monopoly pieces on a game board.

What students need right now is caring adults in the building to be able to support them, she said. That's what's not happening.

Read more here:
Bill introduced to increase provincial control over education - BarrieToday

For the first time since last year's mass shooting at Robb Elementary School in Uvalde, Texas lawmakers considered several bills supporters say could reduce gun violence.

Many Uvalde victims' family members gathered at the Texas Capitol on Tuesday to testify in favor of House Bill 2744, which would increase the age to buy a semiautomatic weapon from 18 to 21.

Veronica Mata, the mother of 10-year-old victim Tess Marie Mata, called on the Legislature to act.

Tess didnt have a choice in life or death," Mata said. "But you as leaders have a choice of what my daughters life will be remembered for."

Mata and the other family members waited more than 12 hours on Tuesday to testify in front of the House Select Committee on Community Safety. Some didn't get a chance to speak until the early hours of Wednesday morning.

Brett Cross lost his 10-year-old Uziyah, and told the panel he's sick of hearing lawmakers say "thoughts and prayers" to him and his family, and not pass legislation that could address gun violence.

"Your thoughts and prayers haven't done anything in the 329 days since Uziyah was shot through his stomach exiting his spine," Cross said. "Your thoughts and prayers are useless unless you have thought and prayed for legislation that you can help enact to change this."

The author of HB 2744, Democratic Rep.Tracy King of Batesville, has never introduced a bill like this before.

King acknowledged he would have voted "no" on a similar bill last session. But the shooting in Uvalde on May 24, 2022, changed his mind.

"The truth is had House Bill 2744 been law in Texas one year ago, 21 constituents of mine ... would still be alive today," King said.

The shooter in the Uvalde school massacre bought two AR-15s days after his 18th birthday.

Other measures debated Tuesday include a pair of proposals that would require sellers to report if a person buys multiple long rifles or firearm magazines in a five-day period.

Tuesday's hearing was rare. Historically, the Texas House hasn't considered gun safety bills like these.

The Legislature has not passed any laws restricting guns after the recent mass shootings in Sutherland Springs, Santa Fe, El Paso or Midland-Odessa.

Rep. Joe Moody, D-El Paso, said several of these mass shootings could have been prevented were some of these proposals in place.

Moody was also part of the House committee that investigated the police response to the Uvalde shooting.

On Tuesday, he told the House Select Committee on Community Safety he saw evidence showing the Uvalde shooter had used blood from the victims to write "LOL" on a white board.

Moody said the Legislature has wasted their time in the past on the issue of curbing gun violence.

"I stood in the House last session to talk about the massacre in El Paso I told everyone then that this was coming to their town and, I'm sorry to say, that it did and it will," Moody said. "This is going to happen again and again if we choose to let it."

Raising the minimum age to 21 is opposed by pro-gun organizations, like the National Rifle Association.

"We represent 18-, 19- and 20-year-olds who are not mass shooters," Tara Mica, a regional lobbyist for the NRA, told the panel Tuesday. "We defend the Constitution."

Mica said proposals to increase the minimum age are likely to be litigated and found unconstitutional.

The Committee will vote on the bill at a later time. However, its future is grim.

Republican lawmakers including Gov. Greg Abbott have said that raising the age would be unconstitutional.

In the Senate, similar bills have not had a single hearing.

Sen. Roland Gutierrez, D-San Antonio, called out Lt. Gov. Dan Patrick for not allowing the bills to be heard in committee.

"We have to get something done," Gutierrez told reporters Tuesday morning. "Let's have this discussion because these families and every other family deserve it."

Go here to read the rest:
Your thoughts and prayers havent done anything: Uvalde families call for changes to Texas gun laws - Houston Public Media

Burhans MS, Hagman DK, Kuzma JN, Schmidt KA, Kratz M. Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus. Compr Physiol. 2019;9:158.

Google Scholar

Zatterale F, Longo M, Naderi J, Raciti GA, Desiderio A, Miele C, et al. Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes. Front Physiol. 2020;10:1607.

Article PubMed PubMed Central Google Scholar

Furman D, Campisi J, Verdin E, Carrera-Bastos P, Targ S, Franceschi C, et al. Chronic inflammation in the etiology of disease across the life span. Nat Med. 2019;25:182232.

Article CAS PubMed PubMed Central Google Scholar

Fasano A. Gut permeability, obesity, and metabolic disorders: Who is the chicken and who is the egg? Am J Clin Nutr. 2017;105:34.

Article CAS PubMed Google Scholar

Piya MK, Harte AL, McTernan PG. Metabolic endotoxaemia: Is it more than just a gut feeling? Curr Opin Lipidol. 2013;24:7885.

Article CAS PubMed Google Scholar

Varma MC, Kusminski CM, Azharian S, Gilardini L, Kumar S, Invitti C, et al. Metabolic endotoxaemia in childhood obesity. BMC Obes. 2016;3:1-8.

Creely SJ, McTernan PG, Kusminski CM, Fisher FM, da Silva NF, Khanolkar M, et al. Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes. Am J Physiol Endocrinol Metab. 2007;292:E7407.

Harte AL, da Silva NF, Creely SJ, McGee KC, Billyard T, Youssef-Elabd EM, et al. Elevated endotoxin levels in non-alcoholic fatty liver disease. J Inflamm. 2010;7:1-10.

Harte AL, Varma MC, Tripathi G, McGee KC, Al-Daghri NM, Al-Attas OS, et al. High fat intake leads to acute postprandial exposure to circulating endotoxin in type 2 diabetic subjects. Diabetes Care. 2012;35:37582.

Article CAS PubMed PubMed Central Google Scholar

Martinez de la Escalera L, Kyrou I, Vrbikova J, Hainer V, Sramkova P, Fried M, et al. Impact of gut hormone FGF-19 on type-2 diabetes and mitochondrial recovery in a prospective study of obese diabetic women undergoing bariatric surgery. BMC Med. 2017;15:1-9.

Bowser SM, Mcmillan RP, Boutagy NE, Tarpey MD, Smithson AT, Osterberg KL, et al. Serum endotoxin, gut permeability and skeletal muscle metabolic adaptations following a short term high fat diet in humans. Metabolism. 2020;103:154041.

Article CAS PubMed Google Scholar

Nascimento EBM, Sparks LM, Divoux A, van Gisbergen MW, Broeders EPM, Jrgensen JA, et al. Genetic Markers of Brown Adipose Tissue Identity and In Vitro Brown Adipose Tissue Activity in Humans. Obesity. 2018;26:13540.

Article CAS PubMed Google Scholar

Al-Amrani A, AbdelKarim M, AlZabin M, Alzoghaibi M. Low expression of brown and beige fat genes in subcutaneous tissues in obese patients. Arch Med Sci. 2019;15:111322.

Article CAS PubMed Google Scholar

Pellegrinelli V, Carobbio S, Vidal-Puig A. Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues. Diabetologia. 2016;59:107588.

Article CAS PubMed PubMed Central Google Scholar

Orava J, Nuutila P, Noponen T, Parkkola R, Viljanen T, Enerbck S, et al. Blunted metabolic responses to cold and insulin stimulation in brown adipose tissue of obese humans. Obesity. 2013;21:227987.

Article CAS PubMed Google Scholar

Chait A, den Hartigh LJ. Adipose Tissue Distribution, Inflammation and Its Metabolic Consequences, Including Diabetes and Cardiovascular Disease. Front Cardiovasc Med. 2020;7:22.

Article CAS PubMed PubMed Central Google Scholar

Bond LM, Ntambi JM. UCP1 deficiency increases adipose tissue monounsaturated fatty acid synthesis and trafficking to the liver. J Lipid Res. 2018;59:22436.

Article CAS PubMed Google Scholar

Matsushita M, Yoneshiro T, Aita S, Kameya T, Sugie H, Saito M. Impact of brown adipose tissue on body fatness and glucose metabolism in healthy humans. Int J Obes (Lond). 2014;38:8127.

Article CAS PubMed Google Scholar

Koksharova E, Ustyuzhanin D, Philippov Y, Mayorov A, Shestakova M, Shariya M, et al. The Relationship Between Brown Adipose Tissue Content in Supraclavicular Fat Depots and Insulin Sensitivity in Patients with Type 2 Diabetes Mellitus and Prediabetes. Diabetes Technol Ther. 2017;19:96102.

Article CAS PubMed PubMed Central Google Scholar

Chondronikola M, Volpi E, Brsheim E, Porter C, Annamalai P, Enerbck S, et al. Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans. Diabetes. 2014;63:408999.

Article CAS PubMed PubMed Central Google Scholar

Leitner BP, Huang S, Brychta RJ, Duckworth CJ, Baskin AS, McGehee S, et al. Mapping of human brown adipose tissue in lean and obese young men. Proc Natl Acad Sci U S A. 2017;114:864954.

Article CAS PubMed PubMed Central Google Scholar

Vijgen GHEJ, Bouvy ND, Teule GJJ, Brans B, Schrauwen P, van Marken Lichtenbelt WD. Brown adipose tissue in morbidly obese subjects. PLoS One. 2011;6:e17247.

Dadson P, Hannukainen JC, Din MU, Lahesmaa M, Kalliokoski KK, Iozzo P, et al. Brown adipose tissue lipid metabolism in morbid obesity: Effect of bariatric surgery-induced weight loss. Diabetes Obes Metab. 2018;20:12808.

Article CAS PubMed Google Scholar

Vijgen GHEJ, Bouvy ND, Teule GJJ, Brans B, Hoeks J, Schrauwen P, et al. Increase in Brown Adipose Tissue Activity after Weight Loss in Morbidly Obese Subjects. J Clin Endocrinol Metab. 2012;97:E122933.

Article CAS PubMed Google Scholar

Hankir MK, Seyfried F. Do Bariatric Surgeries Enhance Brown/Beige Adipose Tissue Thermogenesis? Front Endocrinol. 2020;11:275.

Article Google Scholar

Adami GF, Carbone F, Montecucco F, Camerini G, Cordera R. Adipose Tissue Composition in Obesity and After Bariatric Surgery. Obes Surg. 2019;29:30308.

Article PubMed Google Scholar

Chen Y, Yang J, Nie X, Song Z, Gu Y. Effects of Bariatric Surgery on Change of Brown Adipocyte Tissue and Energy Metabolism in Obese Mice. Obes Surg. 2018;28:82030.

Article PubMed Google Scholar

Okla M, Wang W, Kang I, Pashaj A, Carr T, Chung S. Activation of Toll-like receptor 4 (TLR4) attenuates adaptive thermogenesis via endoplasmic reticulum stress. J Biol Chem. 2015;290:2647690.

Article CAS PubMed PubMed Central Google Scholar

Gavald-Navarro A, Moreno-Navarrete JM, Quesada-Lpez T, Cair M, Giralt M, Fernndez-Real JM, et al. Lipopolysaccharide-binding protein is a negative regulator of adipose tissue browning in mice and humans. Diabetologia. 2016;59:220818.

Article PubMed Google Scholar

Mahdaviani K, Benador IY, Su S, Gharakhanian RA, Stiles L, Trudeau KM, et al. Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis. EMBO Rep. 2017;18:112338.

Article CAS PubMed PubMed Central Google Scholar

Tilokani L, Nagashima S, Paupe V, Prudent J. Mitochondrial dynamics: Overview of molecular mechanisms. Essays Biochem. 2018;62:34160.

Article PubMed PubMed Central Google Scholar

Jornayvaz FR, Shulman GI. Regulation of mitochondrial biogenesis. Essays Biochem. 2010;47:6984.

Article CAS PubMed Google Scholar

Ferree A, Shirihai O. Mitochondrial dynamics: The intersection of form and function. Adv Exp Med Biol. 2012;748:1340.

Article CAS PubMed PubMed Central Google Scholar

Pearce SF, Rebelo-Guiomar P, DSouza AR, Powell CA, Van Haute L, Minczuk M. Regulation of Mammalian Mitochondrial Gene Expression: Recent Advances. Trends Biochem Sci. 2017;42:62539.

Article CAS PubMed PubMed Central Google Scholar

Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and -cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:4129.

Article CAS PubMed Google Scholar

Friedewald WT, Levy RI, Fredrickson DS. Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge. Clin Chem. 1972;18:499502.

Article CAS PubMed Google Scholar

McTernan PG, Anwar A, Eggo MC, Barnett AH, Stewart PM, Kumar S. Gender differences in the regulation of P450 aromatase expression and activity in human adipose tissue. Int J Obes. 2000;24:87581.

Article CAS Google Scholar

Kusminski CM, Da Silva NF, Creely SJ, Fisher FM, Harte AL, Baker AR, et al. The in vitro effects of resistin on the innate immune signaling pathway in isolated human subcutaneous adipocytes. J Clin Endocrinol Metab. 2007;92:2706.

Article CAS PubMed Google Scholar

Schindelin J, Arganda-Carreras I, Frise E, Kaynig V, Longair M, Pietzsch T, et al. Fiji: an open-source platform for biological-image analysis. Nat Methods. 2012;9:67682.

Article CAS PubMed Google Scholar

Jackisch L, Murphy AM, Kumar S, Randeva H, Tripathi G, McTernan PG. Tunicamycin-Induced Endoplasmic Reticulum Stress Mediates Mitochondrial Dysfunction in Human Adipocytes. J Clin Endocrinol Metab. 2020;105:290518.

Article Google Scholar

Tong DL, Boocock DJ, Dhondalay GKR, Lemetre C, Ball GR. Artificial Neural Network Inference (ANNI): A Study on Gene-Gene Interaction for Biomarkers in Childhood Sarcomas. PLoS ONE. 2014;9:e102483.

Article PubMed PubMed Central Google Scholar

Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 2003;13:2498504.

Article CAS PubMed PubMed Central Google Scholar

IBM Corp. Released 2012. IBM SPSS Statistics for Windows, Version 21.0. Armonk, NY: IBM Corp; 2012.

Google Scholar

Yeo CR, Agrawal M, Hoon S, Shabbir A, Shrivastava MK, Huang S, et al. SGBS cells as a model of human adipocyte browning: A comprehensive comparative study with primary human white subcutaneous adipocytes. Sci Rep. 2017;7:4031.

Article PubMed PubMed Central Google Scholar

Pisani DF, Barquissau V, Chambard JC, Beuzelin D, Ghandour RA, Giroud M, et al. Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytes. Mol Metab. 2018;7:3544.

Article CAS PubMed Google Scholar

Villarroya F, Cereijo R, Gavald-Navarro A, Villarroya J, Giralt M. Inflammation of brown/beige adipose tissues in obesity and metabolic disease. J Intern Med. 2018;284:492504.

Article CAS PubMed Google Scholar

Cui X-B, Chen S-Y. White adipose tissue browning and obesity. 2017. https://doi.org/10.7555/JBR.31.20160101.

Beiroa D, Imbernon M, Gallego R, Senra A, Herranz D, Villarroya F, et al. GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK. Diabetes. 2014;63:334658.

Article CAS PubMed Google Scholar

Cero C, Lea HJ, Zhu KY, Shamsi F, Tseng Y-H, Cypess AM. 3-Adrenergic receptors regulate human brown/beige adipocyte lipolysis and thermogenesis. JCI Insight. 2021;6:e139160.

Melby CL, Paris HL, Foright RM, Peth J. Attenuating the Biologic Drive for Weight Regain Following Weight Loss: Must What Goes Down Always Go Back Up? Nutrients. 2017;9.

Bae J, Ricciardi CJ, Esposito D, Komarnytsky S, Hu P, Curry BJ, et al. Activation of pattern recognition receptors in brown adipocytes induces inflammation and suppresses uncoupling protein 1 expression and mitochondrial respiration. Am J Physiol Cell Physiol. 2014;306:C91830.

Article CAS PubMed Google Scholar

Nhr MK, Bobba N, Richelsen B, Lund S, Pedersen SB. Inflammation downregulates UCP1 expression in brown adipocytes potentially via SIRT1 and DBC1 interaction. Int J Mol Sci. 2017;18.

Okla M, Zaher W, Alfayez M, Chung S. Inhibitory Effects of Toll-Like Receptor 4, NLRP3 Inflammasome, and Interleukin-1 on White Adipocyte Browning. Inflammation. 2018;41:62642.

Article CAS PubMed Google Scholar

van Marken Lichtenbelt WD, Schrauwen P. Implications of nonshivering thermogenesis for energy balance regulation in humans. Am J Physiol Regul Integr Comp Physiol. 2011;301:R28596.

Wikstrom JD, Mahdaviani K, Liesa M, Sereda SB, Si Y, Las G, et al. Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure. EMBO J. 2014;33:41836.

CAS PubMed PubMed Central Google Scholar

View post:
The impact of metabolic endotoxaemia on the browning process in ... - BMC Medicine