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DGAP-News: 4SC AG / Key word(s): Miscellaneous Press Release: 4SC presents summary of biomarker and patient subgroup analysis of prognostic factors for survival in advanced HCC

30.09.2013 / 07:30

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Press Release

4SC presents summary of biomarker and patient subgroup analysis of prognostic factors for survival in advanced HCC

- Baseline and biomarker characteristics of advanced HCC patients identified that have an impact on overall survival (OS) and are suitable as enrollment or stratification criteria in upcoming pivotal HCC programme with resminostat

- Novel potentially predictive biomarker ZFP64 identified in both, in HCC and in Hodgkin Lymphoma (HL) patients: high baseline expression of ZFP64 observed in about 2/3 of patients correlates with doubling of median OS under resminostat treatment compared to low ZFP64 expression

- Pharmacodynamic activity of resminostat on ZFP64 confirmed in patients and cell lines: HDAC inhibition by resminostat treatment leads to down-regulation of ZFP64, in peripheral blood of HCC patients

- Further information about proposed role of biomarker ZFP64 in HCC tumour progression presented

- Poster presentation at ECCO 2013 conference, 30 Sept. 2013, Amsterdam

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DGAP-News: Press Release: 4SC presents summary of biomarker and patient subgroup analysis of prognostic factors for ...

The Associated Press President Barack Obama pauses while making a statement regarding the budget fight in Congress and foreign policy challenges, Friday, Sept. 27, 2013, in the James Brady Press Briefing Room of the White House in Washington. (AP Photo/Charles Dharapak)

AP/September 28, 2013

WASHINGTON (AP) President Barack Obama is asking Americans for help spreading the word about new health insurance exchanges.

The exchanges opening Tuesday were created by Obamas health care law. In his weekly radio and Internet address, Obama says Americans can comparison shop like they would for a television or an airplane ticket.

Many, he says, will see cheaper prices and be eligible for tax credits.

Obama says its disturbing Republicans want to shut down the government if he doesnt gut the law. He says the exchanges will open Tuesday no matter what.

In the Republican address, Rep. Cathy McMorris Rodgers of Washington says the president wants to take the easy way out by raising the debt ceiling without cutting spending. She says its is a golden opportunity to fix problems coming from Washington.

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Online:

Obama address: http://www.whitehouse.gov

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Obama asks public to spread word about health law

By GEOFF MULVIHILL Associated Press

A judge's ruling Friday that New Jersey must allow gay couples to marry will not be the last word on the issue after Gov. Chris Christie's administration said it would appeal to a higher court.

The judge, Mary Jacobson, sided with gay and lesbian couples and a gay rights group that argued the state government is violating New Jersey's constitution by denying federal benefits to the couples by not letting them marry. She said the state must allow gay couples to wed starting Oct. 21.

The ruling was the first of its kind in any state court relying on a June U.S. Supreme Court ruling that struck down key parts of a law that blocked the federal government from granting benefits to gay couples.

"Every day that the state does not allow same-sex couples to marry, plaintiffs are being harmed," Jacobson wrote, citing specifically same-sex couples who include a federal employee, those who want to use the federal Family Medical Leave Act or those who file joint federal tax returns.

Whatever course Christie chose had the potential of putting the Republican governor in a tough spot politically.

He's seeking re-election in a state where polls show broad support for gay marriage and where the Legislature passed a law last year to allow it. At the same time, he's seen as a possible contender for the Republican nomination for president in 2016 - a position that requires winning over relatively conservative Republican electorates in some states with early primaries.

Still, he has been resolute about his position, favoring civil unions and opposing gay marriage.

On Friday, Christie refused to take questions about the ruling, instead issuing a brief statement through a spokesman.

"Gov. Christie has always maintained that he would abide by the will of the voters on the issue of marriage equality and called for it to be on the ballot this Election Day," said spokesman Michael Drewniak. "Since the Legislature refused to allow the people to decide expeditiously, we will let the Supreme Court make this constitutional determination."

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NJ legal battle over gay marriage will continue

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Posted on Sep 27, 2013 | Por el personal

NASHVILLE (BP) -- Baptist Press ha nombrado a Shawn Hendricks en el puesto de editor jefe a partir del 28 de octubre.

Hendricks ha sido editor jefe de Biblical Recorder, revista de noticias de la Convencin Bautista Estatal de Carolina del Norte, desde 2011 y fue escritor principal de la Junta de Misiones Internacionales cuando se uni al personal de Recorder. Fue escritor en IMB durante casi 10 aos, 2002-11, y atendi asignaciones en ms de 20 pases.

Hendricks tambin trabaj como escritor de noticias y crnicas del diario de noticias State Gazette en Dyersburg, Tennesse, 1997-98; escritor del personal de relaciones pblicas en Hannibal-LaGrange University en Hannibal, Missouri, 1998-99; y escritor de noticias y crnicas en la antigua revista noticiosa Missouri Baptist Word & Way, 1999-2002.

Graduado en 1996 en periodismo y reas de comunicacin de Union University en Jackson, Tennessee, Hendricks complet su internado en el Indiana Baptist, revista noticiosa de la Convencin Bautista Estatal de Indiana, y en el diario de noticias Jackson Sun (Tennessee). l es oriundo de Troy, Missouri.

Hendricks reemplaza a Michael Foust, quien en julio se convirti en editor de Off The Grid News, un sitio de noticias web propiedad de cristianos con sede en Illinois. Foust sirvi en Baptist Press durante 10 aos, primero como editor asistente y luego como editor asociado.

Baptist Press (www.baptistpress.com y @baptistpress) es el servicio de noticias de la Convencin Bautista del Sur. Es una asignacin del ministerio del Comit Ejecutivo de la CBS.

Roger S. ("Sing") Oldham, vicepresidente de comunicaciones y relaciones de la convencin en el Comit Ejecutivo, anunci la seleccin de Hendricks el 23 de septiembre. Hendricks "trae una amplia experiencia y demostradas habilidades periodsticas a este puesto de Baptist Press," dijo Oldham. "l es un dotado escritor y editor. Est igualmente cmodo en los medios sociales y fortalecer nuestra habilidad de involucrar a lectores jvenes con contenido de calidad. Anticipamos un continuo crecimiento cuando Shawn trabaje en Baptist Press contando la apremiante historia del trabajo cooperativo y colaborador del Reino de los bautistas del sur."

El editor de Baptist Press, Art Toalston dijo que Hendricks personifica "el periodismo de primera clase junto con la aptitud por sus variantes en constante evolucin; una aguda percepcin del corazn para las misiones y el evangelismo de los bautistas del sur; y un corazn para el crecimiento espiritual dondequiera que el Seor gue. Esperamos con ansia que Shawn expanda el gran trabajo que Michael Foust llev a cabo durante sus 10 aos en Baptist Press."

Al unirse al personal de Baptist Press, Hendricks dijo: "Ser un privilegio continuar reportando sobre misiones, ministerio y otros importantes eventos en este pas y en todo el mundo

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Shawn Hendricks se incorpora a Baptist Press